Retinol Binding Protein 4 in Non Obese Psoriatic Cases
نویسندگان
چکیده
منابع مشابه
Retinol-Binding Protein 4 in Twins
OBJECTIVE Retinol-binding protein (RBP) 4 is an adipokine of which plasma levels are elevated in obesity and type 2 diabetes. The aims of the study were to identify determinants of plasma RBP4 and RBP4 mRNA expression in subcutaneous adipose tissue (SAT) and skeletal muscle and to investigate the association between RBP4 and in vivo measures of glucose metabolism. RESEARCH DESIGN AND METHODS ...
متن کاملRetinol-binding protein 4 in human obesity.
Studies in mice suggest that adipocytes serve as glucose sensors and regulate systemic glucose metabolism through release of serum retinol-binding protein 4 (RBP4). This model has not been validated in humans. RBP4 was highly expressed in isolated mature human adipocytes and secreted by differentiating human adipocytes. In contrast to the animal data, RBP4 mRNA was downregulated in subcutaneous...
متن کاملassociation of plasma retinol binding protein-4 (rbp4) and sonographic grading of fatty liver in obese iranian children
results rbp4 levels in obese children (19 482.9 ± 3 302.2 pg/ml) were higher than those found in the lean control group (14 295.68 ± 2 381.3 pg/ml) (p < 0.05). in the obese patients, rbp4 levels showed a significant correlation with the grade of fatty liver and bmi (p < 0.05). conclusions it was found that the level of rbp4 had a strong correlation with the severity of fatty liver. therefore, r...
متن کاملAssociation of Serum Retinol Binding Protein 4 with Atherogenic Dyslipidemia in Morbid Obese Patients
Retinol binding protein 4 (RBP4) is an adipokine that may contribute to the development of insulin resistance. However, how this adipokine is affected and its possible involvement in lipid metabolism in obese patients with varying degrees of insulin resistance is yet to be determined. A total of 299 middle-aged morbid obese patients (BMI>40 kg/m(2)) were divided in euglycemic, metabolic syndrom...
متن کاملParallel downregulation of retinol-binding protein-4 and adiponectin expression in subcutaneous adipose tissue of non-morbidly obese subjects.
CONTEXT AND OBJECTIVE Adipokines are involved in the etiopathology of obesity-related disorders. Since the role of adipokine retinol-binding protein-4 (RBP4) in obesity remains uncertain and its relationship with other adipokines and inflammatory markers has not been examined in detail, we investigated the relationships of RBP4 mRNA expression and circulating protein levels with obesity, anthro...
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ژورنال
عنوان ژورنال: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
سال: 2016
ISSN: 2249-782X
DOI: 10.7860/jcdr/2016/21724.8369